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Fiber Optic Solution
Rainbow Dynamic Dissolution Monitor (RDDM)
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The RainbowPLUS™ is the newest model of the Rainbow Dynamic Dissolution Monitor System (RDDM), which utilizes a patented in situ technology and innovative fiber optic probe, which has become the technology of choice by analytical chemists working in USP dissolution (ie: formulation, method development, and Quality Control). The RDDM is powered by the versatile Indigo™ software, which enables users to perform multiple functions in one integrated system. Furthermore, the RainbowPLUS™ is GMP and 21 CFR Part 11 ready with the IndigoSAM™ secure account manager add-on to Indigo™.
The Rainbow Dynamic Dissolution Monitor System is a powerful tool to aid those requiring multiple, accurate dissolution analyses performed with minimal operator involvement. The RDDM can be used in conjunction with all major dissolution baths used in pharmaceutical laboratories, including Pharma-Test, VanKel, Distek, Hanson, Erweka, Logan and Sotax. Since the RDDM can simultaneously be used as a dissolution monitor, spectrophotometer, and data analyzer, it is no longer necessary to run dissolution on one system, transfer the sample to another system for analysis (UV spectrophotometer or HPLC), and then process the data and analyze results on a third system. The Rainbow Dynamic Dissolution Monitor System will help you conduct dissolution studies faster, with lower overhead costs, and the peace of mind that in situ, fiber optic monitoring provides.
The Rainbow easily accommodates high amounts of turbidity. Turbidity or light scattering from excipients in dosage forms, interferes with the accurate measurement of drugs in solution. The patented data processing algorithm of the Rainbow Dynamic Dissolution Monitor effectively compensates for the spectral effects of turbidity.
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U Flux
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| This unique, novel design will allow you to easily conduct small volume, in situ concentration monitoring, and at the same time evaluate the absorption potential of your compound as you separate the receiver and donor chambers with a membrane. The uFLUX™ also allows you to control for temperature and stirring.uFlux |
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uDiss Profiler
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Spectra Dissolution Monitor
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The Spectra is the newest, next generation model in the Rainbow Dynamic Dissolution Monitor family, which utilizes patented in situ technology and fiber optic probes. The instrument builds upon our experience in the design, development and manufacture of the Rainbow™ and uDiss Profiler fiber optic instruments. Feedback from R&D and process control laboratories was an integral part of the development of this new instrument.
While the Spectra is price competitive with on-line sipper-based systems, it is free of the well-known problems associated with clogged filters, kinked lines and pump maintenance. The Spectra offers real time data collection and the high data density which provides a much greater level of statistical confidence in the dissolution measurements. Since the fiber optic probe remains in the solution throughout the dissolution test, no operator involvement is required. Up to 8 dissolution vessels may be monitored simultaneously within an extended UV-Vis range between 200-700 nm. A xenon lamp provides consistent, stable light output suitable for sustained release applications lasting many weeks or months. As with the reliable Rainbow RDDM, the Spectra is also powered by versatile Indigo software, providing users with multiple functions in one flexible, easy-to-use, integrated system for method development. Furthermore, theIndigoSAM secure account manager software add-on to Indigo™ provides GMP and 21 CFR 11 compatibility for the quality control laboratory. The Spectra is rapidly set up, requires minimal operator involvement during the run, provides real-time data display and is nearly maintenance-free. It is used with any make Dissolution Tester. Spectra will help you conduct dissolution studies faster, with lower overhead costs, and the peace of mind that in situ, fiber optic monitoring provides. The Spectra also easily accommodates high amounts of turbidity. Turbidity or light scattering from excipients in dosage forms, interferes with the accurate measurement of drugs in solution. The patented data processing algorithm effectively compensates for the spectral effects of turbidity. |
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