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Dissolution Testers
Dissolution Testers
14 Station Dissolution System with Syringe Pump
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- 14 Station Dissolution System with Syringe Pump and Sample Collector
- 14 station dissolution testing
- Complies with current USP specifications
- Performs 2 stages of a dissolution test simultaneously, thus saves considerable time
- Essential tool for ANDA and bio-waiver tests
- Effective system for bio-equivalence studies
- Total of 288 samples can be collected (24 x 12)
Features of Syringe Pump (Model: ESP-124)
1. Performs key operations like diluting and mixing samples up to 1:25, filtering, storing and replacing withdrawn samples with fresh media
2. The glass/Teflon syringes eliminate adsorption and offer a high accuracy of dosing (better than +/- 1%)
3. No routine calibration or maintenance
4. Supports 10 ml and 25 ml syringes
5. The high suction capability enables efficient use of fine inline disk type syringe filters (0.45 microns) eliminating manual filtration process
6. The 4-way motorized valve offers unprecedented system flexibility and the capability to deal with sticky media
7. The ergonomically designed syringe pump has a very small footprint to save bench space
Features of Sample Collector (Model: ESC- 12D)
1. The x-y arm movement meets all the automated sampling requirements such as collecting, mixing, aspirating and diluting the samples
2. The diving mechanism pierces the septas of vials to prevent evaporative losses
3. Special sensor detects the alignment and type of tray used to prevent any human errors
4. Completely covered to prevent contamination and air drafts which cause excess evaporation of the collected samples
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Offline Dissolution System
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- The most versatile system, since the samples can be analysed on any UV or HPLC
- Performs all the operations like filtration, storage, replenishment and dilution
- Offers 2 types of rinse options to ensure significant removal of carryover in the transfer tube:
Recirculates the media from test vessel through the transfer tube
2. Split Rinse TM:
Programmed volume of media from test vessel is purged through the transfer tube to waste in multiple cycles
- A cleaning cycle is initiated at the end of every test to ensure all contact parts remain clean before the next test
- Validation cycle is provided for verification of sample, rinse, replenishment and diluent volume
- The sampling manifold dives the cannulas at 16 pharmacopoeia-specific sampling positions in addition to user specified positions
- Performs key operations like diluting and mixing samples up to 1:25, filtering, storing and replacing withdrawn samples with fresh media
- The glass/Teflon syringes eliminate adsorption and offer a high accuracy of dosing (better than +/- 1 %)
- No routine calibration or maintenance
- Supports 10 ml and 25 ml syringes
- The high suction capability enables efficient use of fine inline disk type syringe filters (0.45 microns) eliminating manual filtration process
- The 4-way motorized valve offers unprecedented system flexibility and the capability to deal with sticky media
- The ergonomically designed syringe pump has a very small footprint to save bench space.
- 8 Station Offline Dissolution System with Syringe Pump and Sample Collector.
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Online Dissolution System
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- Supports closed and open loop configurations. In open loop the sampled media is purged to waste with the option to replenish the sampled volume with fresh media
- The high suction capability of the syringe pump enables the efficient use of fine inline filters
- Shortest sampling intervals of 3 min
- Controlled by Electrolab's ElabDisso dissolution software
- Supports Shimadzu UV-1700, UV-1800 and Analytic Jena Specord(R) 205/210 UV spectrophotometers with 8 cell changer
Features of Syringe Pump (Model: ESP-84)
- Performs key operations like diluting and mixing samples up to 1:25, filtering, storing and replacing withdrawn samples with fresh media
- The glass/Teflon syringes eliminate adsorption and offer a high accuracy of dosing (better than +/- 1 %)
- No routine calibration or maintenance
- Supports 10 ml and 25 ml syringes
- The high suction capability enables efficient use of fine inline disk type syringe filters (0.45 microns) eliminating manual filtration process
- The 4-way motorized valve offers unprecedented system flexibility and the capability to deal with sticky media
- The ergonomically designed syringe pump has a very small footprint to save bench space
- 8 Station Online Dissolution System with Syringe Pump and UV Spectrophotometer.
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8 Station Dissolution Tester
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- Complies with USP, IP, Ph. Eur. and JP specifications
- Larger LCD of 40 characters and 4 lines for user friendly operation
- Automatic stirrer height positioning for USP 1, 2, 5, 6, intrinsic test methods and also allows user specified height
- Easy Snap-FitTM shaft locking mechanism for positive engagement and wobble free operation
- Clear water bath with composite top-plate
- Precise individual vessel centering system
- Adjustable leveling of instrument
- Vibration free smooth motorized lift movement
- Isolated water circulating pump for precise temperature control of the water bath
- 20 programmable protocols
- 24 programmable sampling intervals
- Easy to empty and clean water bath with bottom drainage
- Instrument accessories like paddles, baskets, jars etc. are laser marked with serial numbers
- Designed to minimize routine validation
- Report for online validation of test, monograph, error log during the test and physical validation
- Programmable wake-up for temperature control
- Programmable sample volume from 1 ml to 99 ml
- Audio-visual indicators for system status
- Power failure detection facility
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Dissolution Testers
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- First integrated solution with a user friendly interface to observe & record the drug dissolution & disintegration behaviour in the dissolution vessel
- Excellent tool to help in evaluation of OOS, OOT, method development & formulation optimization
- Capacity to record over 1000 hours continuous video
- Simultaneously capture images at pre-programmed intervals for easy sharing & observation of dissolution / disintegration rate
- Remote viewing of the dissolution process via browser enabled network PC
- Adjustable tilt and positioning of cameras at desired height of the vessel
- BlackOut option with amber color light for light sensitive drugs
- compatible with most makes of Dissolution Testers across the globe
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Online Dissolution System
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- Supports various types of glass vials and tubes
- Supports multiple configurations with rinsing capability
- Accurately samples and replenishes the programmed sample volume from each vessel and delivers it to a 6 x 12 fraction collector
- Rinse cycle is programmable to ensure carryover removal from the tubes
- Supports closed loop configuration with 8 cell changer
- seamless integration of electrolab's EDissoTM Software along with Agilent's dissolution software to control the system
- Supports up to 4 dissolution baths for onling dissolution test with single UV spectrophotometer
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14 Station (EDT-14Lx)
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Product Details:
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- 14 station dissolution testing
- Complies with USP, IP, Ph. Eur. specifications
- Supports USP I, USP II, USP V and USP VI test methods
- Ideal for sustained and controlled release products
- Good tool for R&D and QC
- Time saving tool for S1, S2, S3
- Requirement for ANDA tests
- Requirement for bio-waivers
- Effective tools for BE studies
- Acrylic water bath with composite top plate
- Magnetically coupled water circulating pump for precise temperature control of the water bath
- Individual vessel centering system
- 20 programmable protocols
- 24 programmable sampling intervals for each protocols
- Motorized telescopic lift
- 20 x 4 character backlit LCD
- Instrument accessories like baskets, paddles and vessels are laser marked
- Adjustable leveling
- Facilitates Online/ Offline automation
- Temperature monitoring of all 14 vessels with motorized diving manifold and tablet input device (optional)
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Reciprocating Dissolution Tester
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- Complies to current USP Apparatus 3 and 7 specifications
- End user can switch between USP 3 and 7n methods within minutes and without any special tools
- Ideal for extended release products or any dosage form requiring release profiling at multiple pH levels
- Select between multiple configuration of rows. Vessels and vessel volume to meet testing needs for both USP 3 and 7 methods
- Large 40x4 alphanumeric display with alphanumeric keyboard for user friendly operation
- Facilitates manual auto sampling
- 20 programmable protocols with 24 sample intervals
- Diprate ranges between 5 to 50 dpm with an accuracy of +/1%
- Temperature range between 300C to 400 with an accuracy of +/0.10C
- Online validation of dpm and temperature
- Reciprocating Dissolution Tester (USP Apparatus 3 and 7 Dissolution Tester ) ERD - 07.
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Manual Syringe Sampler with adjustable cannulas
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- Adjustable cannulas (to comply with USP requirements) for manual sampling with Leur lock to attach syringes
- Pre-filters can be attached to the tip of the cannula to prevent coarse particles from leaving the media during sampling
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8 Station (EDT-08Lx)
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Product Details:
| Brand | Electrolab |
| Model Name/Number | EDT-08Lx |
| Power | 220/230 VAC, 50/60 Hz, 1.3 kW/6 Amp 110 VAC, 50/60 Hz, 1.3 kW/6 Amp |
| Capacity | Bath capacity 25 |
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Dissolution Tester
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Product Details:
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- Complies with USP requirements
- 2 litre media capacity in each vessel
- For study of poorly soluble drugs
- 8 Station Dissolution Tester
- LCD (20 x 4 lines)
- Menu driven software with Online help
- Precise individual vessel centering system
- Sturdy bath top plate with clear moulded bath
- Temperature control wake-up (Heater turns on at a preset clock time)
- 24 programmable sample intervals and 20 programmable monographs
- Validation print-out with summary of test
- Power failure recovery
- Volume adjustable from 1 ml to 99 ml
- Vibration free, smooth electrical lift movement
- Auto-calibration of temperature
- Reduces routine validation
- Audio-visual status and error indication
- Online validation of RPM
- Instrument leveling system
- 1 litre Conversion kit is also available
- 8 Station Dissolution Tester with 2 litre vessel (EDT - 208Lx).
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Dissolution Tester
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Product Details:
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- To evaluate poorly soluble drugs
- For level 2 pooled dissolution
- For bolus tablets
- For testing veterinary products
- 2 litre and 1 litre conversion kit also available
- 6 Station Dissolution Tester with 4 litre vessel (EDT - 406Lx).
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21 CFR Part 11 Compliant ElabDisso Dissolution Software
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automation of the dissolution test as well as calculate dissolution results and generate reports.
Salient Features :
- Configuration system such as basic, online, offline and online offline
- User friendly creation and loading of test methods
- Programmable pre-run run and post-run sequences
- Real time display of tables and
- Real time display of tables and graphs ofr percentage of dissolution. Absorbance and concertration in addition to instrument status
- Performs statistical analysis such as mean, min., max., standard deviation and percentage relative standard deviation.
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12 Station Dissolution Tester with Timer
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- Three set of paddle/basket running at programmable different RPM
- Calibrated vessel centering and stirrer positions
- Five programmable sample intervals
- Quick interchange between USP I and USP II methods of testing
- Ideal for development of sustained and controlled release products
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